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Medchemexpress LLC Itacitinib | 1334298-90-6 | 100.0% | 553.51 | 500 MG

Supplier: Medchemexpress LLC HY16997500MG
Itacitinib (INCB039110) is an orally active and selective inhibitor of JAK1 with an IC50 of 2 nM for human JAK1. Itacitinib shows >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2; Itacitinib is used in the research of myelofibrosis.
- Orally active and selective inhibitor of JAK1
- IC50 of 2 nM for human JAK1
- >20-fold selectivity for JAK1 over JAK2
- >100-fold selectivity for JAK1 over JAK3 and TYK2
- Used in the research of myelofibrosis
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