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Apexbio Technology LLC ITD 1 1099644-42-4 5mg
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Supplier:  Apexbio Technology LLC B58585

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ITD-1 (CAS 1099644-42-4) is a selective inhibitor of transforming growth factor beta (TGF ) signaling TGF plays a critical role in early cardiac development particularly during the formation of endocardial cushions which give rise to cardiac valves ITD-1 promotes the degradation of the TGF type II receptor thereby modulating TGF -mediated pathways In vitro studies have demonstrated that ITD-1 specifically enhances mesodermal differentiation into cardiomyocytes from embryonic stem cells without promoting differentiation into vascular smooth muscle or endothelial cells ITD-1 serves as a valuable tool for investigating mesoderm and cardiac lineage specification in stem cell research

Catalog No. 50-224-0114


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