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Medchemexpress LLC Itraconazole-d5 | 1217510-38-7 | 99.55% | 710.66 | 1 MG
Supplier: Medchemexpress LLC HY17514S1MG
Itraconazole-d5 is the deuterium labeled Itraconazole. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibiting the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. For research use only. We do not sell to patients.
- Compound can be used as a tracer.
- Compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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