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Apexbio Technology LLC Ivabradine HCl 148849-67-6 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B13605.1
Ivabradine hydrochloride (CAS 148849-67-6) is a selective inhibitor of the If (funny) current in sinoatrial node cells By targeting the If channel Ivabradine reduces cardiac pacemaker activity leading to a dose-dependent decrease in heart rate without affecting myocardial contractility In vitro studies report an IC50 of 2 9 M for inhibition of the If current Owing to its specific action on heart rate modulation Ivabradine HCl is widely utilized in preclinical research investigating cardiac electrophysiology autonomic regulation and the development of heart rate lowering agents
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