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TARGETMOL CHEMICALS INC Ivabradine hydrochloride 200MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T2535200MG

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Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50 2.9 uM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, with negative chronotropic activity. Upon administration, ivabradine selectively binds to the intracellular portion of the HCN channel pore and blocks HCN channels in the pacemaker cells within the sinoatrial (SA) node. This inhibits the If (funny) pacemaker ion current, prevents the inward flow and intracellular accumulation of positively charged ions, reduces pacemaker activity and slows diastolic depolarization. Purity 99.73%

Catalog No. 50-287-6171


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