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Apexbio Technology LLC Ivermectin 70288-86-7 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A28135.1
Ivermectin is a positive allosteric modulator of neuronal nicotinic acetylcholine receptors ( 7 nAChR) and purinergic receptors (P2X4) Additionally ivermectin influences chloride ion channels regulated by glutamate and GABA and also enhances glycine receptor-mediated currents at low concentrations It is commonly employed in neuropharmacological research examining receptor function ion channel activity and neurotransmitter signaling pathways As an anthelmintic ivermectin is widely used in parasitology research for its inhibition of parasite neuromuscular transmission Reported IC50 values vary among receptor types generally ranging from nanomolar to micromolar levels depending on assay conditions and biological context
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