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Apexbio Technology LLC Ivermectin B1a(Synonyms: Ivermectin, 22,23-Dihydroavermectin B1a, Avermectin B1a, MK-933, Stromectol, Mectizan), 5mg, CAS: 71827-03-7.
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Catalog No. 5000061390
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Ivermectin B1a (CAS 71827-03-7) is the primary constituent ( 80%) of the antiparasitic macrocyclic lactone ivermectin Its pharmacological effects originate from selective interaction with glutamate-gated chloride ion channels prevalent in neurons and pharyngeal muscles of nematodes This binding induces durable chloride influx causing sustained hyperpolarization or depolarization resulting in neuromuscular paralysis Ivermectin displays potent antiparasitic efficacy (EC 104 nM) and is clinically significant in treating human onchocerciasis reducing symptoms associated with the infection

Catalog No. 50-000-61390 Supplier Apexbio Technology LLC Supplier No. C39055
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Ivermectin B1a (CAS 71827-03-7) is the primary constituent ( 80%) of the antiparasitic macrocyclic lactone ivermectin Its pharmacological effects originate from selective interaction with glutamate-gated chloride ion channels prevalent in neurons and pharyngeal muscles of nematodes This binding induces durable chloride influx causing sustained hyperpolarization or depolarization resulting in neuromuscular paralysis Ivermectin displays potent antiparasitic efficacy (EC 104 nM) and is clinically significant in treating human onchocerciasis reducing symptoms associated with the infection

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