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Medchemexpress LLC Iwp-o1 | 2074607-48-8 | 99.8% | 432.48 g·mol-1 | C26H20N6O | 10 MG
Supplier: Medchemexpress LLC HY10085310MG
IWP-O1 is a small-molecule porcupine (PORCN) inhibitor used in research to block Wnt protein secretion and signaling. It demonstrates high potency in cell-based assays and suppresses phosphorylation of downstream signaling proteins, making it useful as a tool compound for Wnt pathway studies.
- Potent porcupine (PORCN) inhibitor; EC50 ~80 pM in L-Wnt-STF cells.
- Inhibits Wnt protein secretion and downstream signaling in cell-based assays.
- Suppresses phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
- High reported purity of 99.8%.
- Molecular formula C26H20N6O; molecular weight 432.48 g·mol-1.
- Store protected from light at 4°C; in solvent, -80°C (6 months) or -20°C (1 month).
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