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Selleck Chemical LLC Ixazomib Citrate (MLN9708) Analogue S2181-10mM/1mL

Supplier: Selleck Chemical LLC S218110MM/1ML
Ixazomib Citrate (MLN9708) Analogue is the analogue of Ixazomib Citrate (MLN9708) from WO2016165677A1 Ixazomib Citrate (MLN9708) immediately hydrolyzed to Ixazomib (MLN2238) the biologically active form on exposure to aqueous solutions or plasma Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic ( 5) site of the 20S proteasome with IC50/Ki of 3 4 nM/0 93 nM in cell-free assays less potent to 1 and little activity to 2 Ixazomib (MLN2238) induces autophagy Phase 3
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