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TARGETMOL CHEMICALS INC JACEOSIDIN 5MG
SDP

Catalog No. 502576868
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity modulates the ERK/ATM/Chk1/2 pathway leading to inactivation of the Cdc2-cyclin B1 complex followed by G2/M cell cycle arrest in endometrial cancer cells. Jaceosidin has immunosuppressive effect through inhibiting T cell proliferation and activation which is closely associated with its potent down-regulation of the IFN-(gamma)/STAT1/T-bet signaling pathway. The pharmacokinetics of Jaceosidin may be dramatically affected by polymorphic CYP1A2 UGT1A1 and UGT1A7 responsible for the metabolism of Jaceosidin or by the coadministration of relevant CYP1A2 or UGT inhibitors or inducers. purity: 99%

Catalog No. 50-257-6868 Supplier TARGETMOL CHEMICALS INC Supplier No. T38245MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity modulates the ERK/ATM/Chk1/2 pathway leading to inactivation of the Cdc2-cyclin B1 complex followed by G2/M cell cycle arrest in endometrial cancer cells. Jaceosidin has immunosuppressive effect through inhibiting T cell proliferation and activation which is closely associated with its potent down-regulation of the IFN-(gamma)/STAT1/T-bet signaling pathway. The pharmacokinetics of Jaceosidin may be dramatically affected by polymorphic CYP1A2 UGT1A1 and UGT1A7 responsible for the metabolism of Jaceosidin or by the coadministration of relevant CYP1A2 or UGT inhibitors or inducers. purity: 99%

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