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CPC Scientific H-Cys-Asp-Asp-Tyr-Tyr-Tyr-Gly-Phe-Gly-Cys-Asn-Lys-Phe-Cys-Arg-Pro-Arg-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific SIGN009A
This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-?B activation.ONE-LETTER SEQUENCE: CDDYYYGFGCNKFCRPRMOLECULAR FORMULA: C93H127N25O26S3MOLECULAR WEIGHT:2107.4STORAGE CONDITIONS: -20 5CRESEARCH AREA: Protein Kinases and PhosphatasesREFERENCES: Nickoloff, B. et al. Cell Death Different. 9, 842 (2002).
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