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AdipoGen Jagged-1 hFc h rec
SDP

Supplier:  AdipoGen AG40A0081C010

Encompass_Preferred

Protein. Signal peptide and extracellular domain of human Jagged-1 HJ1 CD339 aa 1-1067 are fused at the C-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in PBS. Purity >90% SDS-PAGE. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis in vitro. Defects in Jagged-1 are the cause of Alagille syndrome type 1 ALGS1 and tetralogy of Fallot TOF.

Catalog No. 50-256-3008


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