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Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.5% | 511.03 | 25 MG
Supplier: Medchemexpress LLC 25MGHY111471A
JAK-IN-5 hydrochloride is an inhibitor of JAK that was extracted from patent US20170121327A1, specifically as compound example 283. It has been shown to inhibit STAT6 phosphorylation by 60% in IL-13-induced lung tissue in a mouse model of pSTAT6 induction. Additionally, in a male C57 mouse model of Alternaria alternata-induced eosinophilic inflammation of the lung, JAK-IN-5 hydrochloride inhibited 88% of BALF eosinophils.
- Inhibitor of JAK.
- Inhibits STAT6 phosphorylation in a mouse model.
- Reduces BALF eosinophils in a mouse model of inflammation.
- For research use only.
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