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Medchemexpress LLC JAK1-IN-4 25mg | 2091134-35-7 | 521.59 | C26H32FN9O2 | 25 MG
SDP

Catalog No. 5000227263
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JAK1-IN-4 is a potent, selective small-molecule inhibitor of Janus kinase 1 used in preclinical research to probe JAK/STAT signaling.

  • Potent JAK1 inhibition, biochemical IC50 85 nM.
  • High selectivity versus JAK2 and JAK3 (IC50 12.8 μM and >30 μM).
  • Cellular activity inhibits STAT3 phosphorylation in NCI-H1975 cells (IC50 227 nM).
  • High chemical purity, 99.26%.
  • Soluble in DMSO at 100 mg/mL (requires sonication).
  • Molecular formula C26H32FN9O2; molecular weight 521.59 g/mol.

Catalog No. 50-002-27263 Supplier Medchemexpress LLC Supplier No. HY11650525MG
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JAK1-IN-4 is a potent, selective small-molecule inhibitor of Janus kinase 1 used in preclinical research to probe JAK/STAT signaling.

  • Potent JAK1 inhibition, biochemical IC50 85 nM.
  • High selectivity versus JAK2 and JAK3 (IC50 12.8 μM and >30 μM).
  • Cellular activity inhibits STAT3 phosphorylation in NCI-H1975 cells (IC50 227 nM).
  • High chemical purity, 99.26%.
  • Soluble in DMSO at 100 mg/mL (requires sonication).
  • Molecular formula C26H32FN9O2; molecular weight 521.59 g/mol.

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