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Medchemexpress LLC Jatrorrhizine hydroxide | 483-43-2 | 355.38 | 20 MG
Supplier: Medchemexpress LLC HYN0749A20MG
Jatrorrhizine hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial, and antioxidant activities. It is a potent and orally active inhibitor of AChE (IC50=872 nM) with over >115-fold selectivity for BuChE. Jatrorrhizine hydroxide reduces the uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters.
- Alkaloid isolated from coptis chinensis
- Exhibits neuroprotective activity
- Shows antimicrobial properties
- Possesses antiplasmodial effects
- Offers antioxidant activities
- Potent and orally active AChE inhibitor
- Highly selective for BuChE over AChE
- Reduces serotonin and norepinephrine uptake
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