Medchemexpress LLC JBJ-09-063 (TFA) | 99.6% | 670.67 | 25 MG

Supplier:  Medchemexpress LLC 25MGHY147183A

JBJ-09-063 TFA is a mutant-selective allosteric EGFR inhibitor that effectively reduces EGFR, Akt, and ERK1/2 phosphorylation. It is effective across EGFR tyrosine kinase inhibitor (TKI)-sensitive and resistant models and can be used for researching EGFR-mutant lung cancer. This inhibitor is remarkably effective at inhibiting cell growth, leading to a significant increase in apoptosis, and exhibits favorable pharmacokinetics properties for good efficacy upon oral dosing.

• Mutant-selective allosteric EGFR inhibitor
• Reduces EGFR, Akt, and ERK1/2 phosphorylation
• Effective against EGFR TKI-sensitive and resistant models
• Suitable for EGFR-mutant lung cancer research
• Inhibits cell growth and increases apoptosis
• Favorable pharmacokinetics properties
• Stable for good efficacy upon oral dosing

Catalog No. 50-003-63128