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Medchemexpress LLC JBSNF-000028 hydrochloride | C11H14ClN3 | 10 MM * 1 ML
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Supplier:  Medchemexpress LLC HY151500B10MM/1ML

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JBSNF-000028 hydrochloride is an orally active small molecule inhibitor of tricyclic nicotinamide N-methyltransferase (NNMT). It shows anti-obesity and anti-diabetic activities and can be used for the study of metabolic diseases such as obesity, type 2 diabetes, and non-alcoholic fatty liver disease.

  • Orally active small molecule inhibitor of tricyclic nicotinamide N-methyltransferase (NNMT)
  • Reduces endogenous MNA levels in U2OS osteosarcoma cells
  • Shows significant anti-obesity and anti-diabetic activities
  • Used for the study of metabolic diseases
  • Improves glucose and lipid handling in mice with diet-induced obesity (DIO)
  • Improves glucose tolerance in NNMT knockout mice with diet-induced obesity

Catalog No. 50-003-74105


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