Dojindo Molecular Technologies Inc JC-1 MitoMP Detection Kit (1 set), easy to dissolve, can be detected by several instruments (Ex=500 nm, Em=530 nm), Imaging Buffer included: keeps the cell condition optimal for a long period.

Supplier:  Dojindo Molecular Technologies Inc MT0910

Mitochondria is one of the important organelles in discussing early cytotoxicity, oxidative stress, and apoptosis in vivo. Mitochondria synthesize ATP using oxygen to produce the necessary energy for living cells. The lowering or dysfunction of mitochondrial activity is known to be closely related to cancer, aging, and neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. JC-1 is widely used for observing mitochondrial membrane potential. JC-1 forms aggregates (in healthy mitochondria) with red fluorescence (590 nm). As membrane potential decreases, JC-1 dissociates into monomers, which show green fluorescence (530 nm).Unlike other commercially available JC-1, no precipitation of JC-1 aqueous buffer occurs by using this kit. In addition, the Image Buffer included in this kit minimizes fluorescent background and maintains cell health during assays. Dojindo offers various reagents for mitochondria research. (https://www.dojindo.com/mitochondria-research/)

Catalog No. NC1960974