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Medchemexpress LLC JC-171 | 2112809-98-8 | MFCD32708504 | 98.4% | 384.83 g/mol | C16H17ClN2O5S | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1174325MG

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JC-171 is a selective NLRP3 inflammasome inhibitor that blocks LPS/ATP-induced interleukin-1β (IL-1β) release from macrophages (IC50 8.45 μM). It is used for in vitro studies of inflammasome activation and for in vivo models of inflammasome-driven inflammation such as experimental autoimmune encephalomyelitis.

  • Selective NLRP3 inflammasome inhibition
  • Effective in macrophage IL-1β release assays (IC50 8.45 μM)
  • Validated in vivo activity in experimental autoimmune encephalomyelitis
  • High purity solid for research use (≈98.4%)
  • Stable as powder under recommended storage conditions
  • Available in small research quantities (e.g., 5 mg)

Catalog No. 50-002-27773


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