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TARGETMOL CHEMICALS INC JERVINE 10MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T336310MG

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Also available in 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed. purity: 99%

Catalog No. 50-257-6958


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