Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC JH-XVI-178 | 2648453-53-4 | 98.9% | 435.91 | 100 MG
Supplier: Medchemexpress LLC HY139875100MG
JH-XVI-178 is a highly efficient and selective inhibitor of CDK8/19, with IC50 values of 1 nM for CDK8 and 2 nM for CDK19. It exhibits a low clearance rate and moderate oral pharmacokinetic properties.
- Highly efficient and selective CDK8/19 inhibitor
- IC50 values of 1 nM for CDK8 and 2 nM for CDK19
- Low clearance rate
- Moderate oral pharmacokinetic properties
- Inhibits the phosphorylation of S727-STAT1 in Jurkat cells
- Tested in mice model via oral administration at 10 mg/kg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?