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Medchemexpress LLC JH295 100mg | 1311143-71-1 | 320.35 g/mol | C18H16N4O2 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY116423100MG

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JH295 is a potent, irreversible, and selective NIMA-related kinase 2 (Nek2) inhibitor for research use. It alkylates Nek2 (Cys22) and shows an IC50 of 770 nM. The compound is a yellow to orange solid (C18H16N4O2, MW 320.35 g/mol) with reported purity ≈98.7%; store at -20°C under nitrogen and prepare fresh solutions due to instability.

  • Selective Nek2 inhibition via covalent alkylation
  • IC50 ~770 nM in biochemical assays
  • Soluble in DMSO (~55 MG/ML); ultrasonic assistance may be required
  • High purity suitable for research (~98.7%)
  • Store at -20°C under inert gas; unstable in solution

Catalog No. 50-002-29153


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