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Medchemexpress LLC JH295 10mg | 1311143-71-1 | 320.35 g/mol | C18H16N4O2 | 10 MG
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Supplier:  Medchemexpress LLC HY11642310MG

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JH295 is a potent, irreversible, and selective NIMA-related kinase 2 (Nek2) inhibitor with a reported IC50 of approximately 770 nM. The compound alkylates a cysteine residue (Cys22) in Nek2 and contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition for bioconjugation. It is supplied as a research reagent for biochemical assays, cellular target validation, and chemical biology applications.

  • Irreversible Nek2 inhibition via cysteine alkylation.
  • Reported IC50 approximately 770 nM.
  • Contains an alkyne for click-chemistry conjugation (CuAAC).
  • High reported purity (~98.7%).
  • Suitable for biochemical assays and chemical biology applications.

Catalog No. 50-002-29268


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