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Medchemexpress LLC JH295 50mg | 1311143-71-1 | 50 MG
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Supplier:  Medchemexpress LLC HY11642350MG

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JH295 is an irreversible, cysteine-targeted inhibitor of NIMA-related kinase 2 (Nek2) used for biochemical and cellular studies. It irreversibly alkylates Cys22, shows an IC50 of approximately 770 nM, and contains an alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition (click chemistry).

  • Irreversible Nek2 inhibitor; IC50 ≈ 770 nM.
  • Cysteine-targeted covalent mechanism (alkylation of Cys22).
  • Contains an alkyne handle for click chemistry applications.
  • Molecular weight 320.35; formula C18H16N4O2.
  • High reported purity (98.66%).
  • Solid, yellow to orange appearance.

Catalog No. 50-002-27989


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