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Medchemexpress LLC JH295 5mg | 1311143-71-1 | 320.35 g/mol | C18H16N4O2 | 5 MG
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Supplier:  Medchemexpress LLC HY1164235MG

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JH295 is a potent, irreversible, and selective NIMA-related kinase 2 (Nek2) inhibitor that contains an alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition (click chemistry). Supplied as a 5 mg quantity at 98.66% purity, the compound has a molecular weight of 320.35 g/mol and formula C18H16N4O2; reported cellular IC50 for Nek2 is 770 nM and the mechanism involves covalent alkylation of Cys22.

  • Irreversible Nek2 inhibitor with reported IC50 of 770 nM.
  • Contains an alkyne group for CuAAc click chemistry.
  • Mechanism involves covalent alkylation of cysteine residue Cys22.
  • Supplied as a 5 mg quantity at 98.66% purity.
  • Molecular weight 320.35 g/mol; chemical formula C18H16N4O2.

Catalog No. 50-002-27148


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