Apexbio Technology LLC Jingzhaotoxin III(Synonyms: Beta-theraphotoxin-Jz3a, β-TRTX-Jz3a, β-theraphotoxin-Jingzhao3a, Jingzhaotoxin-III), 100ug, CAS: 925463-91-8.

Supplier:  Apexbio Technology LLC B57630.1

Jingzhaotoxin III (CAS 925463-91-8) is a selective inhibitor of the voltage-gated sodium channel Nav1 5 a protein primarily expressed in cardiac myocytes and crucial for cardiac electrophysiological activity Jingzhaotoxin III blocks Nav1 5 channels with an IC50 of approximately 0 348 M demonstrating a rapid-onset and reversible inhibition that is concentration-dependent showing complete inhibition at 1 03 M Animal studies indicate its capability to reduce both frequency and severity of arrhythmias suggesting its utility in cardiac arrhythmia research and associated therapeutic exploration

Catalog No. 50-000-60418