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Medchemexpress LLC JMV 2959 hydrochloride | 2448414-54-6 | 545.08 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHYU00433A

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JMV 2959 hydrochloride is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist. It exhibits an IC50 of 32±3 nM in LLC-PK1 cells for GHS-R1a and does not induce intracellular calcium mobilization by itself.

  • GHS-R1a antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
  • Dissociation constant (Kb) for the receptor complex is 19±6 nM.
  • Decreases acoustic startle responses (ASR) and increases prepulse inhibition (PPI) in vivo.
  • Blocks Phencyclidine (PCP)-induced deficits in PPI.

Catalog No. 50-004-49813


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