Medchemexpress LLC JNJ-1013 | 2597343-08-1 | 99.8% | 878.05 g/mol | C46H55N9O7S | 10 MG

Supplier:  Medchemexpress LLC HY15318810MG

JNJ-1013 is a research-grade PROTAC degrader that selectively targets interleukin-1 receptor-associated kinase 1 (IRAK1). It induces IRAK1 degradation, modulates downstream signaling, and has been characterized in cellular assays for apoptosis and pathway inhibition. Supplied as a high-purity solid, it is intended for in vitro biochemical and cellular studies.

• Potent IRAK1 activity with reported IC50 values: 72 nM (IRAK1), 443 nM (IRAK4), 1,071 nM (VHL FP).
• High reported purity (99.8%).
• Molecular weight 878.05 g/mol; formula C46H55N9O7S.
• Soluble in DMSO at 25 mg/mL; may require warming or sonication.
• Recommended storage: protect from light at 4°C; in solution store at -80°C for long-term or -20°C up to one month.
• Suitable for in vitro target validation, signaling pathway studies, and apoptosis assays.

Catalog No. 50-002-85749