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Medchemexpress LLC JNJ-1661010 (Takeda-25) | 681136-29-8 | 5 MG
Supplier: Medchemexpress LLC HYN70625MG
JNJ-1661010, also known as Takeda-25, is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). It exhibits IC50 values of 34 nM for rat FAAH and 33 nM for human FAAH. This compound is capable of crossing the blood-brain barrier and is utilized as a broad-spectrum analgesic.
- Potent and selective FAAH inhibitor
- Crosses the blood-brain barrier
- Acts as a broad-spectrum analgesic
- Shows apparent inhibition of human FAAH in CHO-K1 cells with an IC50 of 11 nM
- Diminishes thermal hyperalgesia in inflammatory rat models
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