Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC JNJ-18038683 | 851376-05-1 | 98.31% | 529.97 | 50 MG
Supplier: Medchemexpress LLC HY1988950MG
JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19 and 8.20 for rat and human 5-HT7 in HEK293 cells. It displaces specific [3H]5-CT binding sites from rat and human 5-HT7 receptor expressed in HEK293 cells with high affinity. In vivo, it dose-dependently suppresses REM sleep.
- High affinity for 5-HT7 receptors (rat and human)
- Antagonizes 5-HT (100 nM)-stimulated adenylyl cyclase activity
- Dose-dependently suppresses REM sleep
- Maintains decreased REM sleep time with repeated administration
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?