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Cayman Chemical JNJ-26481585 (hydrochloride), Purity: ≥98%, CAS: 875320-31-3, 1 mg
SDP

Catalog No. 502953661
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A pan-HDAC inhibitor; inhibits class I (IC50s = 0.11-4.86 nM for HDAC1-3 and HDAC8, respectively), inhibits class IIa (IC50s = 0.64-119 nM for HDAC4-5 and HDAC7-9), and class IIb HDACs (IC50s = 76.8 and 0.46 nM for HDAC6 and HDAC10, respectively), as well as the class IV HDAC HDAC11 (IC50 = 0.37 nM); induces apoptosis, pyroptosis, and ferroptosis in CAL-27 and Tca8113 cells at 200 nM; completely inhibits tumor growth in HCT116 Ras mutant and C170HM2 mouse xenograft models at 10 mg/kg once per day

Catalog No. 50-295-3661 Supplier Cayman Chemical Supplier No. 140881 MG
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A pan-HDAC inhibitor; inhibits class I (IC50s = 0.11-4.86 nM for HDAC1-3 and HDAC8, respectively), inhibits class IIa (IC50s = 0.64-119 nM for HDAC4-5 and HDAC7-9), and class IIb HDACs (IC50s = 76.8 and 0.46 nM for HDAC6 and HDAC10, respectively), as well as the class IV HDAC HDAC11 (IC50 = 0.37 nM); induces apoptosis, pyroptosis, and ferroptosis in CAL-27 and Tca8113 cells at 200 nM; completely inhibits tumor growth in HCT116 Ras mutant and C170HM2 mouse xenograft models at 10 mg/kg once per day

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