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Medchemexpress LLC JNJ 303 | 878489-28-2 | 98.7% | 440.98 | 5 MG
SDP

Catalog No. 5000390714
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JNJ-303 is a specific delayed rectifier Kv blocker that can potently inhibit IKs with an IC50 value of 64 nM. It is indicated for research related to diabetes, obesity, and the central nervous system.

  • Specific delayed rectifier Kv blocker.
  • Potently blocks IKs with an IC50 value of 64 nM.
  • Can be utilized for research on diabetes, obesity, and the central nervous system.
  • At a concentration of 3.3 μM, JNJ 303 shows no effects on other cardiac channels.
  • It has been observed to induce QT-prolongations and unprovoked torsades de pointes (TdP).
  • In mice, JNJ 303 recapitulates the Exn4-induced reduction in fasting blood glucose levels.

Catalog No. 50-003-90714 Supplier Medchemexpress LLC Supplier No. HY169535MG
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JNJ-303 is a specific delayed rectifier Kv blocker that can potently inhibit IKs with an IC50 value of 64 nM. It is indicated for research related to diabetes, obesity, and the central nervous system.

  • Specific delayed rectifier Kv blocker.
  • Potently blocks IKs with an IC50 value of 64 nM.
  • Can be utilized for research on diabetes, obesity, and the central nervous system.
  • At a concentration of 3.3 μM, JNJ 303 shows no effects on other cardiac channels.
  • It has been observed to induce QT-prolongations and unprovoked torsades de pointes (TdP).
  • In mice, JNJ 303 recapitulates the Exn4-induced reduction in fasting blood glucose levels.

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