Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502978384

Cayman Chemical JNJ-38158471, Purity: ≥98%, CAS: 951151-97-6, 5 mg
SDP

Catalog No. 502978384
Encompass_Preferred

A VEGFR2 inhibitor (IC50 = 42 nM); selective for VEGFR2 over FMS, PDGFRα, FLT3, and KIT (IC50s = 624, 1,109 nM, 4,810, and 511 nM, respectively) and VEGFR1 and VEGFR3 (IC50s = 4,451 and 1,112 nM, respectively) but does inhibit RET (IC50 = 183 nM); decreases VEGF-induced phosphorylation of VEGFR2 in serum-starved HUVECs at 10, 100, or 500 nM; inhibits VEGF-induced migration in HUVECs at 1 µM; reduces Vegf-induced corneal neovascularization in mice at 100 mg/kg; decreases tumor size in an HCT116 mouse xenograft model at 10-200 mg/kg per day; reduces polyp number in an Apc+/Min-FCCC mouse model of spontaneous colorectal adenoma at 100 mg/kg per day

Catalog No. 50-297-8384 Supplier Cayman Chemical Supplier No. 413615 MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

A VEGFR2 inhibitor (IC50 = 42 nM); selective for VEGFR2 over FMS, PDGFRα, FLT3, and KIT (IC50s = 624, 1,109 nM, 4,810, and 511 nM, respectively) and VEGFR1 and VEGFR3 (IC50s = 4,451 and 1,112 nM, respectively) but does inhibit RET (IC50 = 183 nM); decreases VEGF-induced phosphorylation of VEGFR2 in serum-starved HUVECs at 10, 100, or 500 nM; inhibits VEGF-induced migration in HUVECs at 1 µM; reduces Vegf-induced corneal neovascularization in mice at 100 mg/kg; decreases tumor size in an HCT116 mouse xenograft model at 10-200 mg/kg per day; reduces polyp number in an Apc+/Min-FCCC mouse model of spontaneous colorectal adenoma at 100 mg/kg per day

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.