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Cayman Chemical JNJ-42756493, Purity: ≥98%, CAS: 1346242-81-6, 5 mg
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Catalog No. 502963997
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A pan-FGFR inhibitor (IC50s = 1.2, 2.5, 3, and 5.7 nM for FGFR1, -2, -3, and -4, respectively); selective for FGFRs over VEGFR2 (IC50 = 36.8 nM); inhibits the proliferation of Ba/F3 cells expressing FGFR1, 3, or 4 (IC50s = 22.1, 13.2, and 25 nM, respectively); reduces tumor growth in a SNU-16 gastric cancer mouse xenograft model at 10 and 30 mg/kg

Catalog No. 50-296-3997 Supplier Cayman Chemical Supplier No. 218135 MG
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A pan-FGFR inhibitor (IC50s = 1.2, 2.5, 3, and 5.7 nM for FGFR1, -2, -3, and -4, respectively); selective for FGFRs over VEGFR2 (IC50 = 36.8 nM); inhibits the proliferation of Ba/F3 cells expressing FGFR1, 3, or 4 (IC50s = 22.1, 13.2, and 25 nM, respectively); reduces tumor growth in a SNU-16 gastric cancer mouse xenograft model at 10 and 30 mg/kg

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