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Medchemexpress LLC Jnj-47117096 hydrochloride | 1610536-69-0 | 99.7% | 398.891 g/mol | C21H23ClN4O2 | 25MG
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Supplier:  Medchemexpress LLC HY1242025MG

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JNJ-47117096 hydrochloride (MELK-T1 hydrochloride) is the hydrochloride salt of a small-molecule kinase inhibitor selective for MELK and active against FLT3. It is used as a research reagent to probe MELK biology and to evaluate antiproliferative effects in cellular assays.

  • Potent MELK inhibition (IC50 23 nM)
  • Also inhibits Flt3 (IC50 18 nM)
  • Shows cellular antiproliferative activity (Ba/F3 cells IC50 ~1.5 μM without IL-3)
  • Provided as a hydrochloride salt to aid solubility in biological assays
  • High chemical purity (~99.7%) and documented CAS identifier (1610536-69-0)

Catalog No. 50-002-36088


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