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Medchemexpress LLC HY-111751 10mg Medchemexpress, JNJ-61432059 CAS:2035814-50-5 Purity:>98%
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Supplier:  Medchemexpress LLC HY11175110MG

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Medchemexpress, HY-111751 10mg JNJ-61432059 CAS:2035814-50-5 JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Catalog No. 50-196-8949


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