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Medchemexpress LLC (+)-JNJ-A07 | 2135640-93-4 | 98.46% | 578.96 | 25 MG
Supplier: Medchemexpress LLC 25MGHY139602C
(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor that targets the NS3-NS4B interaction. It demonstrates nanomolar to picomolar activity against 21 clinical isolates and exhibits a favorable pharmacokinetic profile, leading to significant efficacy against dengue virus infection in mouse models.
- Targets NS3-NS4B interaction
- Potent pan-serotype dengue virus inhibitor
- Effective against 21 clinical isolates
- Favorable pharmacokinetic profile
- High barrier to resistance
- Inhibits viral replication complex formation
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