Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC (+)-JNJ-A07 | 2135640-93-4 | 98.5% | 578.96 | 1 ML
Supplier: Medchemexpress LLC HY13960210MM/1ML
(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor that targets the NS3-NS4B interaction. It exhibits nanomolar to picomolar activity against 21 clinical isolates and possesses a favorable pharmacokinetic profile, leading to outstanding efficacy against dengue virus infection in mouse models. It also demonstrates a high barrier to resistance and prevents the formation of the viral replication complex by blocking the interaction between two viral proteins (NS3 and NS4B).
- Targets the NS3-NS4B interaction
- Highly potent and orally active
- Pan-serotype dengue virus inhibitor
- Effective against 21 clinical isolates
- Favorable pharmacokinetic profile
- Outstanding efficacy in mouse models
- High barrier to resistance
- Prevents viral replication complex formation
- Suitable for infection and viral infection research
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?