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Medchemexpress LLC (+)-JNJ-A07 | 2135640-93-4 | 98.5% | 578.96 | 25 MG
SDP

Catalog No. 5000349912
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(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor that targets the NS3-NS4B interaction. It demonstrates nanomolar to picomolar activity against a panel of 21 clinical isolates. The compound possesses a favorable pharmacokinetic profile, leading to outstanding efficacy against dengue virus infection in mouse infection models.

  • Exhibits a high barrier to resistance
  • Prevents the formation of the viral replication complex by blocking the interaction between two viral proteins (NS3 and NS4B)
  • Potent and orally active pan-serotype dengue virus inhibitor
  • Effective against a panel of 21 clinical isolates
  • Favorable pharmacokinetic profile
  • Outstanding efficacy against dengue virus infection in mouse models

Catalog No. 50-003-49912 Supplier Medchemexpress LLC Supplier No. 25MGHY139602
May include imposed supplier surcharges.
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(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor that targets the NS3-NS4B interaction. It demonstrates nanomolar to picomolar activity against a panel of 21 clinical isolates. The compound possesses a favorable pharmacokinetic profile, leading to outstanding efficacy against dengue virus infection in mouse infection models.

  • Exhibits a high barrier to resistance
  • Prevents the formation of the viral replication complex by blocking the interaction between two viral proteins (NS3 and NS4B)
  • Potent and orally active pan-serotype dengue virus inhibitor
  • Effective against a panel of 21 clinical isolates
  • Favorable pharmacokinetic profile
  • Outstanding efficacy against dengue virus infection in mouse models

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