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Sigma Aldrich Jones Reagent

Catalog No. 75803525ML Shop All MilliporeSigma Sigma Organic Chemistry Products
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75-803-525ML 25 mL
75-803-5100ML 100 mL
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Jones reagent is a solution of chromium trioxide in aqueous sulfuric acid. Using acetone as a reaction solvent, the reagent is usually used for the oxidation of primary and secondary alcohols to carboxylic acids and ketones, respectively.The oxidation is very rapid and exothermic. The reagent tolerates a variety of functionalities, such as, for example, unsaturated bonds, which are rarely oxidized.For a comprehensive review of chromium-based reagents, see Oxidation of Alcohols to Aldehydes and Ketones by Tojo and Fern+fndez, Springer Berlin, 2006, 1-97.Jones reagent can be used:In the oxidative cleavage of various alkenes into carboxylic acids and ketones using a catalytic amount of osmium tetroxide.To prepare symmetrical binaphthols by oxidative dehydrodimerization of substituted naphthols.To synthesize acyl-naphthols and substituted isocoumarins from 2-(4-hydroxy-but-1-ynyl)benzaldehydes.

Specifications

CAS 65272-70-0
Density 1.298 g/mL at 25°C
Quantity 25 mL
MDL Number MFCD22199316
Synonym Jone's reagent; Chromium trioxide solution in sulfuric acid; Sulfuric acid-chromium trioxide mixture
Biological Activity Respiratory System
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