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Cayman Chemical JP1302hydroCLOrID hydrat 10mg
Supplier: Cayman Chemical 2597410 MG
An α2C-AR antagonist; selective for α2C-ARs over α2A- and α2B-ARs (Kis = 28, 3,150, and 1,470 nM, respectively); reduces immobility time in the forced swim test in mice at 1, 3, and 10 μmol/kg; reverses phencyclidine-induced decreases in prepulse inhibition of the acoustic startle response in rat at 5 mg/kg; dose-dependently reduces haloperidol-induced bradykinesia and catalepsy in mice; increases systolic blood pressure in rats at 0.3 mg/kg
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