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Cayman Chemical Juglns regIa L. JuglaIn 10mg

Supplier: Cayman Chemical 3982410 MG
A flavonol with diverse biological activities; reduces OSS-induced increases in ROS in HAECs at 2.5 and 5 µM; inhibits the proliferation of, as well as induces JNK activation, autophagosome formation, apoptosis, and cell cycle arrest at the G2/M phase in, MCF-7 human breast cancer cells at 2.5, 5, and 10 µM; reduces tumor growth in an MCF-7 mouse xenograft model at 10 and 20 mg/kg; reduces body weight, renal fibrosis, and blood glucose levels, as well as serum and renal levels of Tnf-α, Il-1β, Il-6, and Ccl2, and improves glucose tolerance in a mouse model of high-fat diet- and obesity-induced kidney disease at 15 and 30 mg/kg
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