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JW 55, Tocris Bioscience™

Catalog Number 451450
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
664993-53-7
C25H26N2O5
434.49
MFCD03863265
ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
n-4-4-4-methoxyphenyl oxan-4-yl methylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl carbamoyl phenyl furan-2-carboxamide, qcr-64, n-4-4-4-methoxyphenyl oxan-4-yl methyl carbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-ylmethylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furamide, n-4-tetrahydro-4-4-methoxyphenyl-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furancarboxamide
2946601
N-[4-({[4-(4-methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamide
COC1=CC=C(C=C1)C1(CNC(=O)C2=CC=C(NC(=O)C3=CC=CO3)C=C2)CCOCC1
This item is not returnable. View return policy
664993-53-7
C25H26N2O5
434.49
MFCD03863265
ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
n-4-4-4-methoxyphenyl oxan-4-yl methylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl carbamoyl phenyl furan-2-carboxamide, qcr-64, n-4-4-4-methoxyphenyl oxan-4-yl methyl carbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-ylmethylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furamide, n-4-tetrahydro-4-4-methoxyphenyl-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furancarboxamide
2946601
N-[4-({[4-(4-methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamide
COC1=CC=C(C=C1)C1(CNC(=O)C2=CC=C(NC(=O)C3=CC=CO3)C=C2)CCOCC1

Tankyrase inhibitor

Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin; inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines; reduces cell cycle progression and proliferation in SW480 cells in vitro.
Quantity 50 mg
Formula Weight 434.48
Percent Purity >98%
Chemical Name or Material JW 55
Recommended Storage Store at +4°C
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