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JW 55, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
664993-53-7
C25H26N2O5
434.492
ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
n-4-4-4-methoxyphenyl oxan-4-yl methylcarbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl carbamoyl phenyl furan-2-carboxamide,qcr-64,n-4-4-4-methoxyphenyl oxan-4-yl methyl carbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-ylmethylcarbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methylcarbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furamide,n-4-tetrahydro-4-4-methoxyphenyl-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furancarboxamide
2946601
N-[4-[[4-(4-methoxyphenyl)oxan-4-yl]methylcarbamoyl]phenyl]furan-2-carboxamide
COC1=CC=C(C=C1)C2(CCOCC2)CNC(=O)C3=CC=C(C=C3)NC(=O)C4=CC=CO4
This item is not returnable. View return policy
664993-53-7
C25H26N2O5
434.492
ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
n-4-4-4-methoxyphenyl oxan-4-yl methylcarbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl carbamoyl phenyl furan-2-carboxamide,qcr-64,n-4-4-4-methoxyphenyl oxan-4-yl methyl carbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-ylmethylcarbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methylcarbamoyl phenyl furan-2-carboxamide,n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furamide,n-4-tetrahydro-4-4-methoxyphenyl-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furancarboxamide
2946601
N-[4-[[4-(4-methoxyphenyl)oxan-4-yl]methylcarbamoyl]phenyl]furan-2-carboxamide
COC1=CC=C(C=C1)C2(CCOCC2)CNC(=O)C3=CC=C(C=C3)NC(=O)C4=CC=CO4

Tankyrase inhibitor

Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin; inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines; reduces cell cycle progression and proliferation in SW480 cells in vitro.
Quantity 50mg
Formula Weight 434.48
Percent Purity >98%
Chemical Name or Material JW 55

Recommended Storage : Store at +4°C