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JW 642, Tocris Bioscience™

Catalog No. 490650
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Catalog No. Quantity
49-065-0 50 mg
49-061-0 10 mg
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Catalog No. 49-065-0 Supplier R&D Systems Supplier No. 4906/50
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Description

MAGL inhibitor

Potent and selective monoacylglycerol lipase (MAGL) inhibitor (IC50 = 3.7 nM). Displays >1000-fold selectivity for MAGL over fatty acid amide hydrolase (IC50 = 20.6 μM). Analog of JZL 195 (Cat. No. 4715).

Chemical Identifiers

CAS 1416133-89-5
Molecular Formula C21H20F6N2O3
Molecular Weight (g/mol) 462.392
InChI Key AVSCNEOUWSVZEY-UHFFFAOYSA-N
Synonym 1,1,1,3,3,3-hexafluoropropan-2-yl 4-3-phenoxybenzyl piperazine-1-carboxylate, 1,1,1,3,3,3-hexafluoropropan-2-yl 4-3-phenoxyphenyl methyl piperazine-1-carboxylate, 4-3-phenoxyphenyl methyl-1-piperazinecarboxylic acid 2,2,2-trifluoro-1-trifluoromethyl ethyl ester
PubChem CID 71656520
IUPAC Name 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylate
SMILES C1CN(CCN1CC2=CC(=CC=C2)OC3=CC=CC=C3)C(=O)OC(C(F)(F)F)C(F)(F)F

Specifications

Color White
Quantity 50 mg
Formula Weight 462.39
Percent Purity >98%
Physical Form Solid
Chemical Name or Material JW 642

Safety and Handling

Recommended Storage Store at -20°C
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