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Cayman Chemical JWH 018 5hydroxyIndl meta 10mg

Supplier: Cayman Chemical 900085210 MG

A histamine H1 receptor antagonist (Ki 15 nM) selective for the histamine H1 receptor over mAChRs (Ki 263 nM) but also inhibits 5-HT2 (Ki 7 nM) inhibits histamine release induced by an anti-IgE antibody in isolated human lung fragments (IC50 4.5 nM) inhibits A23187-induced degranulation of RBL-2H3 mast cells inhibits LPS-induced NO production in RAW 264.7 cells at 50 UM and fMLP- or PMA-induced superoxide production in isolated rat neutrophils reduces histamine-induced vascular permeability in mice (ED50 2.9 mg/kg)
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