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Cayman Chemical JWH 081 5methoxynaphthyl1mg

Supplier: Cayman Chemical 90010461 MG

A PAI-1 inhibitor (IC50 655 nM) selective for PAI-1 over tPA and plasminogen as well as a panel of 40 neurotransmitter endocrine and enzymatic targets at 10 UM enhances cleavage of monomeric and oligomeric AB42 in a cell-free assay at 5 UM reduces plasma AB40 and brain AB40 and AB42 levels in the Tg2576 transgenic mouse model of Alzheimer’s disease at 20 mg/kg reverses cognitive deficits in the same model at 30 and 100 mg/kg
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