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Cayman Chemical K-7174hydrochlorIde 5mg

Supplier: Cayman Chemical 327735 MG
A 20S proteasome inhibitor; inhibits the 20S proteasome β1, β2, and β5 catalytic subunits at 5 µM; reduces TNF-α- or IL-1β-induced adherence of U937 monocytes to HUVECs at 10 µM; inhibits tumor growth in U266 and RPMI-8226 multiple myeloma mouse xenograft models at 75 mg/kg; an inhibitor of the GATA consensus sequence
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