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Medchemexpress LLC K-80003 | 1292821-90-9 | 336.40 | 50 MG
Supplier: Medchemexpress LLC HYU0045850MG
K-80003 is a potent inhibitor of tRXRα-dependent Akt activation and cancer cell growth. It demonstrates high affinity to RXRα and lacks COX inhibitory activity, displaying enhanced efficacy in inhibiting tRXRα-dependent AKT activation and tumor growth in animals.
- Inhibits TNFα-induced colocalization of tRXRα with p85α
- Stabilizes tetrameric tRXRα in the nuclear fraction
- Potent inhibitor of AKT activation
- Enhanced efficacy in inhibiting tRXRα-dependent AKT activation and tumor growth in animals
- High affinity to RXRα
- Lacks COX inhibitory activity
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