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LifeSensors K48-Linked Tetra-Ubiquitin (Phosphorylated) 25µg

Supplier: LifeSensors SI4804P0025
K48 chains traditionally play a role in proteasomal degradation pathways. Phospho-ubiquitin chains represent a specialized class of polyubiquitin characterized by phosphorylation at Serine 65 and play a central role in mitophagy signaling pathways. K48 Tetra-Ubiquitin (Phosphorylated) is a tetrameric chain of wild-type ubiquitin, wherein ubiquitin monomers are linked together via an isopeptide bond between Lysine 48 and the C-terminal Glycine. The chains are then enzymatically phosphorylated at the Ser65 position.
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