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  7. Kaempferol, 98+%, Thermo Scientific Chemicals

Kaempferol, 98+%, Thermo Scientific Chemicals

Catalog No. AAJ60373MF
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AAJ60373MF 50 mg
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Catalog No. AAJ60373MF Supplier Thermo Scientific Chemicals Supplier No. J60373MF
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Description

Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

Solubility
Soluble in DMSO or ethanol to 100mM

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep away fom strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 520-18-3
Molecular Formula C15H10O6
Molecular Weight (g/mol) 286.24
MDL Number MFCD00016938
InChI Key IYRMWMYZSQPJKC-UHFFFAOYSA-N
Synonym kaempferol, kaempherol, kempferol, populnetin, rhamnolutein, robigenin, trifolitin, pelargidenolon, rhamnolutin, swartziol
PubChem CID 5280863
ChEBI CHEBI:28499
SMILES OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1

Specifications

Melting Point 276°C to 278°C
Color Yellow
Quantity 50 mg
Beilstein 304401
Merck Index 14,5274
Solubility Information Soluble in DMSO or ethanol to 100mM
IUPAC Name 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Formula Weight 286.24
Percent Purity ≥98%
Physical Form Powder
Chemical Name or Material Kaempferol
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Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 208-287-6
RTECSNumber LK9275200
TSCA No
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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